AssayIndex
Impurities & degradation

Oxidation

Addition of oxygen. Methionine to sulfoxide (+15.995) then sulfone (+31.990); tryptophan to oxindole and beyond; cysteine to sulfonic acid.

Related terms

Sulfoxide
The +15.995 Da methionine oxidation product. Elutes earlier than the parent on reverse phase. A handling finding, not a synthesis finding.
see also Oxidation
Oxidation ladder
The series of peaks from sequential oxidation of multiple oxidisable residues: parent, mono-sulfoxide, bis-sulfoxide. Diagnostic — a single early peak with no second rung is probably something else.
see also Oxidation

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.