Terms beginning with F
5 of 238 glossary terms.
- Fill weight
- The gross mass of material in a vial as weighed. Not the peptide mass — it includes water, counter-ion and residual solvent.
- Fibrillation
- Ordered self-assembly into amyloid-like fibrils. Glucagon is the fastest fibrillator in this index; native amylin is why pramlintide exists.
- Fmoc
- Fluorenylmethyloxycarbonyl, the standard temporary amine protecting group in solid-phase synthesis. Residual Fmoc appears at +222.068 Da.
- Forced degradation
- Deliberately stressing a sample under acid, base, oxidative, thermal and photolytic conditions to prove the method can resolve degradants.
- Freeze–thaw
- Repeated freezing and thawing of a reconstituted solution. A common aggregation trigger and a standard forced-degradation stress.
see also Label claim · Recovered mass
see also Aggregate
see also Stability-indicating method
see also Aggregate · Forced degradation