Capping
Deliberately acetylating unreacted amines during synthesis so failed couplings terminate as short capped species rather than continuing as deletion sequences.
Related terms
- Acetylation
- Addition of an acetyl group, +42.011 Da. Either a deliberate synthesis capping step or an unwanted side reaction.
- Deletion sequence
- A peptide missing one or more residues from an incomplete coupling. Mass difference equals the missing residue mass. A synthesis finding: it does not form in a vial.
see also Capping
see also Coupling efficiency · Truncation
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 23 glossary terms beginning with C