AssayIndex
Impurities & degradation

Disulfide scrambling

Cysteines paired in an incorrect combination. Mass-identical to correct pairing and only detectable by peptide mapping or comparison against a folded reference.

Related terms

Open-chain form
A cyclic peptide with its disulfide reduced, +2.016 Da. A handling artefact, resolved chromatographically, and functionally inactive.

Where this term appears

The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.