GC headspace
Gas chromatography of the vapour above a heated sealed sample. The standard technique for residual solvents.
Related terms
- Residual solvent
- Process solvent remaining in the product. DMF, DMSO, acetonitrile and dichloromethane are the usual candidates in peptide synthesis. Controlled by ICH Q3C.
see also Mass balance · GC headspace
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 8 glossary terms beginning with G