Aib
α-Aminoisobutyric acid. An achiral, sterically hindered residue used to resist enzymatic cleavage. Present in every incretin co-agonist in this index; its hindered couplings drive epimerisation nearby.
Related terms
- Epimerisation
- Inversion of a single stereocentre during synthesis, typically during carboxyl activation. Produces a diastereomer.
- Diastereomer
- A stereoisomer arising from inversion at one chiral centre. Same formula, same mass, same UV spectrum, often much less active. The impurity no mass spectrum finds.
see also Diastereomer · Racemisation
see also Epimerisation · Racemisation
Where this term appears
The glossary exists to make record pages readable without a chemistry degree. Every technical term on a report resolves here.
- Assay report records — the term appears in result tables, peak tables and provenance blocks
- Method references — where the measurement behind the term is defined
- All 17 glossary terms beginning with A