Cross-section

Liraglutide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Liraglutide, with a class minimum gradient of 25 min, the method is a live explanation.

154 recordsmedian 99.02 %spec 97.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	72	30min	High	98.74	+0.00	98.74	ADEQUATE
Medutest	30	25min	Unit	99.07	+0.08	98.99	ADEQUATE
PeptideMeter	22	28min	High	99.25	-0.05	99.30	ADEQUATE
Kestrel	12	15min	Unit	99.82	+0.24	99.58	BELOW CLASS MINIMUM
VendorInvestigate	9	32min	High	98.69	-0.11	98.80	ADEQUATE
Nordanalyt	9	35min	High	99.23	+0.02	99.21	ADEQUATE

Figure. Liraglutide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.