AssayIndex

GGPE-2509-T2530

MK-677 (Ibutamoren mesylate) · 250 mg declared · Nantong Guangyuan Chemical Co., Ltd. · manufactured 19 Sep 2025

CHARACTERISED
Lot code
GGPE-2509-T2530
Supplier
GGPeps — Nantong Guangyuan Chemical Co., Ltd.
Compound
MK-677 (Ibutamoren mesylate)
Compound class
Non-peptide adjuncts
Declared label claim
250mg
Manufacture date
19 Sep 2025
Index quarter
2026-Q1
Independent assays
11
Laboratories involved
Janoshik, Medutest, PeptideMeter, Nordanalyt
Provenance mix
Supplier-supplied ×9 · Laboratory-retained ×2
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 11
Median purity 99.48% n=11
Spread (max − min) 0.91pp n=11
Standard deviation 0.283pp n=11
96.997.498.098.599.199.6100.2This lot (GGPE-2509-T2530)This lot (GGPE-2509-T2530): Q1 99.26, median 99.48, Q3 99.57, n=11n=11All MK-677 (Ibutamoren mesylate)All MK-677 (Ibutamoren mesylate): Q1 98.51, median 99.37, Q3 99.77, n=152n=152 Purity (% area)
Figure 1. This lot's independent purity results against the whole MK-677 (Ibutamoren mesylate) record set in the index. The vertical line is the index acceptance specification for the non-peptide adjuncts class, 98.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 11

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042872GGPE-2509-T2530Janoshik2026-Q199.414.0295.2Supplier-supplied1FAIL
AX-2026-042873GGPE-2509-T2530Janoshik2026-Q199.533.77Supplier-supplied1FAIL
AX-2026-042874GGPE-2509-T2530Medutest2026-Q198.904.1095.4Laboratory-retained1FAIL
AX-2026-042875GGPE-2509-T2530PeptideMeter2026-Q199.814.3793.3Supplier-supplied0FAIL
AX-2026-042876GGPE-2509-T2530Nordanalyt2026-Q199.483.8298.1Supplier-supplied1FAIL
AX-2026-042877GGPE-2509-T2530Janoshik2026-Q199.493.7491.9Supplier-supplied0FAIL
AX-2026-042878GGPE-2509-T2530Janoshik2026-Q198.983.99Laboratory-retained1FAIL
AX-2026-042879GGPE-2509-T2530Nordanalyt2026-Q199.614.26Supplier-supplied1FAIL
AX-2026-042880GGPE-2509-T2530PeptideMeter2026-Q199.113.7089.2Supplier-supplied2FAIL
AX-2026-042881GGPE-2509-T2530PeptideMeter2026-Q199.614.30107.5Supplier-supplied0FAIL
AX-2026-042882GGPE-2509-T2530Janoshik2026-Q199.474.13Supplier-supplied1FAIL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik599.41, 99.53, 99.49, 98.98, 99.4799.4730min+0.0099.47
Medutest198.9098.9025min+0.0898.82
PeptideMeter399.81, 99.11, 99.6199.6128min-0.0599.66
Nordanalyt299.48, 99.6199.5535min+0.0299.53

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.6499.41divergence +0.16 pp vs batch median
Total impurities (% area)0.360.59
Largest single impurity (% area)not stated0.36
Water (%)3.24.02
Counter-ion (%)6.113.91
Peptide content (%w/w)90.181.91
Endotoxin (EU/mg)not statednot determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
sulfonamide hydrolysis product (+18 Da)11 / 110.140.10–0.35
residual DMF (process solvent)11 / 110.110.03–0.17
spiroindane regioisomer10 / 110.320.07–0.47
O-desmethyl metabolite analogue (−14 Da)8 / 110.050.04–0.07
free base (des-mesylate, −96 Da)6 / 110.070.05–0.10
Section 7

What this rollup does not establish