AX-2026-043637

CJC-1295 (no DAC) · 10 mg declared · PolyPeptide Group (Hangzhou) Co., Ltd. · lot PPG-2512-D7211

PASSPURITY ONLY

Report ID: AX-2026-043637
Compound: CJC-1295 (no DAC)
Compound class: Growth-hormone axis peptides
Supplier: PPG — PolyPeptide Group (Hangzhou) Co., Ltd.
Batch / lot: PPG-2512-D7211
Declared label claim: 10mg
Laboratory: Kestrel Bioanalytical
Assay date: 05 Apr 2026
Submitted: 14 Apr 2026
Quarter: 2026-Q2
Submitter: an.aguirre
Sample provenance: Buyer-sourced

Section 1

Results

Measured against the index acceptance specification for the growth-hormone axis peptides class. A specification is a decision the index made; a result is a measurement. See where each threshold came from.

Parameter	Method	Result	Unit	Index spec
Purity	RP-HPLC, 15 min gradient, 214 nm	99.88	% area	≥ 98.0	PASS
Total impurities	RP-HPLC, sum of reported peaks	0.12	% area	≤ 2.0	PASS
Largest single impurity	RP-HPLC — des-Tyr1 (−163 Da)	0.07	% area	≤ 1.00	PASS
Identity	not ordered on this submission	not determined	—	required for VERIFIED status	NOT TESTED
Peptide content	not ordered on this submission	not determined	—	required to check label claim	NOT TESTED
Water content	Karl Fischer, coulometric, duplicate	4.50	%	≤ 9.0	PASS
Counter-ion (acetate)	anion-exchange ion chromatography	4.72	%	≤ 12.0	PASS
Residual solvent + inorganic residue	estimated — see /methods/residual-solvents-q3c/	0.56	%	—	NOT TESTED
Endotoxin	not ordered on this submission	not determined	—	≤ 5.0	NOT TESTED
Sterility	not ordered on this submission	not determined	—	no growth	NOT TESTED
Appearance	visual, diffuse light, black and white background	Off-white lyophilised cake, intact	—	white to off-white intact cake	PASS
Reconstitution clarity	reconstituted per submitter procedure	Clear, colourless, no visible particulates	—	clear, no visible particulates	PASS
pH (reconstituted, 1 mg/mL)	potentiometric, two-point calibration	5.43	—	2.5 – 8.0	PASS
Retention time (observed)	RP-HPLC, 15 min gradient	7.05	min	6.94 ± 0.30 (normalised)	PASS
Peak asymmetry (10 % height)	Ph. Eur. 2.2.46	1.28	—	0.80 – 1.50	PASS
Plate count, main peak	N = 5.54 (t/w½)²	71,079	—	≥ 20,000	PASS
Resolution to nearest impurity	vs native GRF (1-29) (−59 Da)	1.57	—	no index criterion	REPORTED

Section 2

Chromatogram and peak integration

The figure is drawn from the table. It is not an independent illustration — if a number in the table changed, the trace would change with it.

Figure 1. RP-HPLC trace, 15 min gradient, 214 nm. Drawn from the peak-integration table below: peak positions are the reported retention times, peak areas are the reported area percentages, peak widths follow the reported plate count of 71,079, and skew follows the reported asymmetry factor of 1.28. Baseline noise is seeded from the report ID and is illustrative. The lower panel is the same trace at a stated vertical expansion with the slow gradient drift subtracted, because at full scale a 0.07 % impurity against a 99.88 % main peak is a line two pixels tall; the main peak runs off-scale there by design.

#	Peak	RT	Area (µV·s)	% area	Δ mass (Da)
1	CJC-1295 (no DAC) — main peak	7.05	4,854,478	99.88	—
2	des-Tyr1 (−163 Da)	6.78	3,402	0.07	-163.063
3	native GRF (1-29) (−59 Da)	6.88	1,458	0.03	-58.995
4	truncated (1-24)	6.47	972	0.02	-570.291
Closure check — purity + Σ impurities				100.00	CLOSES

Reporting threshold 0.05 % area. Peaks below it are not reported and are therefore excluded from the total, which overstates purity by their sum — see peak integration.

Section 4

Gravimetric mass balance

Water, counter-ion, residual and total peptide content are exhaustive and mutually exclusive categories. They must account for 100 % of the cake mass. The index closes this to within 0.02 pp and the build asserts it.

Supplier certificate, as declared

The supplier's own figures for this lot, beside the independent measurement. Divergence is assessed against the batch median, not against this single report — see rule AX-R05.

Figure	Supplier COA	This report	Index note
Purity (% area)	99.87	99.88	divergence +0.22 pp vs batch median
Total impurities (% area)	not stated	0.12
Largest single impurity (% area)	not stated	0.07
Water (%)	3.4	4.50
Counter-ion (%)	not stated	4.72
Peptide content (%w/w)	91.8	not determined
Endotoxin (EU/mg)	0.21	not determined
Method stated on certificate	YES	—	column, gradient and wavelength given

Section 5

Provenance and caveats

Where a sample came from changes the weight of the evidence. The index treats it as a first-class field.

Sample provenance: Buyer-sourced
Evidentiary weight: Strongest available evidence in this index.
Chain of custody: Retail purchase → submitter (ambient, 15 d) → laboratory (hand-carried, 3 d) → assay.
Assay date: 05 Apr 2026
Submitted to the index: 14 Apr 2026
Laboratory: Kestrel Bioanalytical, Melbourne, Australia
Method basis: 15 min gradient · unit-resolution MS
Verification status: PURITY ONLY

What this report does not establish

That the compound is the compound named. No identity confirmation was ordered on this submission. A purity figure describes chromatographic homogeneity of whatever eluted; it does not name it.
How much of the named compound is in the vial. Peptide content was not determined, so recovered mass cannot be calculated and the label claim cannot be checked.
That the material is free of bacterial endotoxin. Endotoxin was not measured. No chromatographic result bears on it.
That the material is sterile. Sterility was not tested.
That any other vial in the same lot has the same composition. One vial was tested. Within-lot vial-to-vial variation in this index has a median of 0.28 pp and a 90th percentile of 0.74 pp.
That any other lot from the same supplier has the same composition. Batch-to-batch variation is larger than within-batch variation for every supplier here.
That the material is suitable for administration to a human or an animal. These are research compounds. No result on this site is a safety assessment and the index takes no position on use.
That the material was manufactured by the supplier that sold it. Contract synthesis is normal in this market and twenty-nine batches in the index fingerprint to a bulk from a different company than the one named on the label.

Section 6

Annotations 2

Signed technical comments from index contributors. Not a discussion forum — annotations question or contextualise the result, and the data team replies where a reply is warranted.

buyer_sourced14 Apr 2026

No relationship between submitter and supplier is declared on this record, and the contributor register holds none. That is the default and it is what the provenance class asserts.

c18_2p614 Apr 2026

Core-shell packing at 2.6 µm gains roughly 40 % in resolution over a 5 µm fully porous bed at the same length and pressure. On a pair this close, that is the difference between two peaks and one.

Section 7

Related records

Same batch — lot PPG-2512-D7211 n=14

Report	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Flags	Result
AX-2026-043624	PPG-2512-D7211	Janoshik	2026-Q2	99.42	4.74	—	Supplier-supplied	0	PASS
AX-2026-043625	PPG-2512-D7211	Janoshik	2026-Q2	99.60	4.82	—	Buyer-sourced	0	PASS
AX-2026-043626	PPG-2512-D7211	Nordanalyt	2026-Q2	99.66	4.94	92.5	Buyer-sourced	0	PASS
AX-2026-043627	PPG-2512-D7211	PeptideMeter	2026-Q2	98.97	5.10	91.9	Buyer-sourced	0	PASS
AX-2026-043628	PPG-2512-D7211	Medutest	2026-Q2	99.71	5.17	89.9	Buyer-sourced	2	MARGINAL
AX-2026-043629	PPG-2512-D7211	Janoshik	2026-Q2	99.67	5.21	95.0	Buyer-sourced	0	PASS
AX-2026-043630	PPG-2512-D7211	Janoshik	2026-Q2	99.66	5.11	92.5	Buyer-sourced	0	PASS
AX-2026-043631	PPG-2512-D7211	Janoshik	2026-Q2	99.55	4.79	95.2	Buyer-sourced	0	PASS
AX-2026-043632	PPG-2512-D7211	Janoshik	2026-Q2	99.60	4.87	92.6	Buyer-sourced	0	PASS
AX-2026-043633	PPG-2512-D7211	Janoshik	2026-Q2	99.64	5.48	—	Buyer-sourced	0	PASS
AX-2026-043634	PPG-2512-D7211	Janoshik	2026-Q2	99.93	5.06	—	Buyer-sourced	0	PASS
AX-2026-043635	PPG-2512-D7211	Medutest	2026-Q2	99.75	4.61	—	Buyer-sourced	0	PASS
AX-2026-043636	PPG-2512-D7211	Janoshik	2026-Q2	99.64	5.31	—	Buyer-sourced	0	PASS

Batch rollup and reproducibility assessment →

Cross-sections

Other recent CJC-1295 (no DAC) records in the index.
Report	Supplier	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Flags	Result
AX-2026-042942	MKM	MKM-2603-V3346	Janoshik	2026-Q3	99.52	3.43	—	Supplier-supplied	0	PASS
AX-2026-041599	QSC	QSC-2606-V7416	VendorInvestigate	2026-Q3	97.96	3.52	—	Buyer-sourced	1	FAIL
AX-2026-042784	GGPeps	GGPE-2606-E1234	Medutest	2026-Q3	98.27	4.55	—	Buyer-sourced	0	PASS
AX-2026-042939	MKM	MKM-2603-V3346	PeptideMeter	2026-Q3	99.44	3.39	—	Buyer-sourced	0	PASS
AX-2026-041601	QSC	QSC-2606-V7416	Kestrel	2026-Q3	98.33	4.10	—	Buyer-sourced	1	MARGINAL
AX-2026-042945	MKM	MKM-2603-V3346	PeptideMeter	2026-Q3	99.39	3.54	—	Laboratory-retained	0	PASS
AX-2026-042786	GGPeps	GGPE-2606-E1234	Janoshik	2026-Q3	98.22	3.77	—	Buyer-sourced	0	PASS
AX-2026-041602	QSC	QSC-2606-V7416	VendorInvestigate	2026-Q3	98.36	3.38	101.8	Buyer-sourced	1	MARGINAL

Other recent PPG records in the index.
Report	Compound	Lot	Lab	Quarter	Purity %	Water %	Recovery %	Provenance	Flags	Result
AX-2026-043598	Tesamorelin	PPG-2608-A6835	Kestrel	2026-Q3	98.91	2.56	100.3	Buyer-sourced	1	FAIL
AX-2026-043597	Tesamorelin	PPG-2608-A6835	Janoshik	2026-Q3	98.54	1.15	—	Buyer-sourced	0	PASS
AX-2026-043596	Tesamorelin	PPG-2608-A6835	PeptideMeter	2026-Q3	98.74	1.83	105.1	Buyer-sourced	1	MARGINAL
AX-2026-043605	Retatrutide	PPG-2604-X7060	Janoshik	2026-Q2	98.17	4.29	99.7	Buyer-sourced	0	PASS
AX-2026-043601	Retatrutide	PPG-2604-X7060	Janoshik	2026-Q2	98.28	3.96	95.3	Buyer-sourced	0	PASS
AX-2026-043668	AOD-9604	PPG-2602-W8018	PeptideMeter	2026-Q2	99.47	3.06	—	Buyer-sourced	0	PASS
AX-2026-043670	AOD-9604	PPG-2602-W8018	PeptideMeter	2026-Q2	99.56	2.71	104.5	Buyer-sourced	0	PASS
AX-2026-043630	CJC-1295 (no DAC)	PPG-2512-D7211	Janoshik	2026-Q2	99.66	5.11	92.5	Buyer-sourced	0	PASS