AssayIndex
Cross-section

Pramlintide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Pramlintide, with a class minimum gradient of 25 min, the method is a live explanation.

33 recordsmedian 98.84 %spec 97.5 %
LaboratoryReportsGradientMS resolutionMedian purity %Published bias (pp)Bias-adjustedMethod suitability
Janoshik1830minHigh98.78+0.0098.78ADEQUATE
PeptideMeter7 n=728minHigh99.10-0.0599.15ADEQUATE
VendorInvestigate3 n=332minHigh98.23-0.1198.34ADEQUATE
Nordanalyt2 n=235minHigh98.99, 98.36+0.02—ADEQUATE
Kestrel2 n=215minUnit99.55, 99.36+0.24—BELOW CLASS MINIMUM
Medutest1 n=125minUnit99.93+0.08—ADEQUATE
97.798.198.598.999.399.7100.1JanoshikJanoshik: Q1 98.60, median 98.78, Q3 99.04, n=18outlier 97.87n=18PeptideMeterPeptideMeter: Q1 98.62, median 99.10, Q3 99.33, n=7n=7VendorInvestigateVendorInvestigate: Q1 98.08, median 98.23, Q3 98.51, n=3n=3NordanalytNordanalyt: Q1 98.52, median 98.67, Q3 98.83, n=2n=2KestrelKestrel: Q1 99.41, median 99.45, Q3 99.50, n=2n=2 Purity (% area)
Figure. Pramlintide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.