Cross-section

MK-677 (Ibutamoren mesylate) by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for MK-677 (Ibutamoren mesylate), with a class minimum gradient of 15 min, the method is a live explanation.

152 recordsmedian 99.37 %spec 98.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	70	30min	High	99.41	+0.00	99.41	ADEQUATE
PeptideMeter	24	28min	High	99.16	-0.05	99.21	ADEQUATE
Medutest	20	25min	Unit	99.21	+0.08	99.13	ADEQUATE
VendorInvestigate	15	32min	High	98.26	-0.11	98.37	ADEQUATE
Nordanalyt	12	35min	High	99.76	+0.02	99.74	ADEQUATE
Kestrel	11	15min	Unit	99.88	+0.24	99.64	ADEQUATE

Figure. MK-677 (Ibutamoren mesylate) purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.