Cross-section

Mazdutide by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for Mazdutide, with a class minimum gradient of 25 min, the method is a live explanation.

33 recordsmedian 98.11 %spec 96.5 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	13	30min	High	98.57	+0.00	98.57	ADEQUATE
PeptideMeter	7 n=7	28min	High	97.94	-0.05	97.99	ADEQUATE
Medutest	6 n=6	25min	Unit	98.36	+0.08	98.28	ADEQUATE
VendorInvestigate	3 n=3	32min	High	97.32	-0.11	97.43	ADEQUATE
Nordanalyt	2 n=2	35min	High	97.61, 97.32	+0.02	—	ADEQUATE
Kestrel	2 n=2	15min	Unit	97.99, 98.11	+0.24	—	BELOW CLASS MINIMUM

Figure. Mazdutide purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.