Cross-section

5-Amino-1MQ by laboratory

The same compound measured by different laboratories on different gradients. Where the medians differ, the question is whether the material differed or the method did — and for 5-Amino-1MQ, with a class minimum gradient of 15 min, the method is a live explanation.

68 recordsmedian 99.24 %spec 98.0 %

Laboratory	Reports	Gradient	MS resolution	Median purity %	Published bias (pp)	Bias-adjusted	Method suitability
Janoshik	35	30min	High	99.27	+0.00	99.27	ADEQUATE
Medutest	11	25min	Unit	99.31	+0.08	99.23	ADEQUATE
PeptideMeter	6 n=6	28min	High	99.56	-0.05	99.61	ADEQUATE
Nordanalyt	6 n=6	35min	High	98.97	+0.02	98.95	ADEQUATE
VendorInvestigate	5 n=5	32min	High	98.77	-0.11	98.88	ADEQUATE
Kestrel	5 n=5	15min	Unit	99.22	+0.24	98.98	ADEQUATE

Figure. 5-Amino-1MQ purity by contributing laboratory. Any offset between rows has two possible sources — a real difference in the material each laboratory happened to receive, and the laboratory's own bias — and this figure cannot separate them. The paired analysis that can is on inter-lab agreement.