AssayIndex

HOMO-2408-A1230

Humanin (HNG) · 10 mg declared · Hunan Aslsen Technology Co., Ltd. · manufactured 12 Aug 2024

CHARACTERISED
Lot code
HOMO-2408-A1230
Supplier
Homopeptide — Hunan Aslsen Technology Co., Ltd.
Compound
Humanin (HNG)
Compound class
Metabolic and mitochondrial peptides
Declared label claim
10mg
Manufacture date
12 Aug 2024
Index quarter
2025-Q1
Independent assays
11
Laboratories involved
Janoshik, PeptideMeter, Medutest, VendorInvestigate
Provenance mix
Buyer-sourced ×2 · Supplier-supplied ×9
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 11
Median purity 99.71% n=11
Spread (max − min) 0.72pp n=11
Standard deviation 0.240pp n=11
96.597.197.898.499.099.6100.2This lot (HOMO-2408-A1230)This lot (HOMO-2408-A1230): Q1 99.51, median 99.71, Q3 99.84, n=11n=11All Humanin (HNG)All Humanin (HNG): Q1 99.14, median 99.47, Q3 99.73, n=42outlier 96.79n=42 Purity (% area)
Figure 1. This lot's independent purity results against the whole Humanin (HNG) record set in the index. The vertical line is the index acceptance specification for the metabolic and mitochondrial peptides class, 97.5 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 11

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-019506HOMO-2408-A1230Janoshik2025-Q199.686.14Supplier-supplied1MARGINAL
AX-2025-019507HOMO-2408-A1230PeptideMeter2025-Q199.465.2691.8Supplier-supplied1MARGINAL
AX-2025-019508HOMO-2408-A1230Janoshik2025-Q199.215.24Buyer-sourced1MARGINAL
AX-2025-019509HOMO-2408-A1230PeptideMeter2025-Q199.935.15Supplier-supplied1MARGINAL
AX-2025-019510HOMO-2408-A1230Janoshik2025-Q199.575.05105.7Supplier-supplied1MARGINAL
AX-2025-019511HOMO-2408-A1230Medutest2025-Q199.935.18Supplier-supplied1MARGINAL
AX-2025-019512HOMO-2408-A1230Janoshik2025-Q199.355.56Supplier-supplied1MARGINAL
AX-2025-019513HOMO-2408-A1230VendorInvestigate2025-Q199.715.27Buyer-sourced1MARGINAL
AX-2025-019514HOMO-2408-A1230Janoshik2025-Q199.745.87Supplier-supplied1MARGINAL
AX-2025-019515HOMO-2408-A1230Janoshik2025-Q199.935.6399.9Supplier-supplied1MARGINAL
AX-2025-019516HOMO-2408-A1230Janoshik2025-Q199.725.87Supplier-supplied1MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik799.68, 99.21, 99.57, 99.35, 99.74, 99.93, 99.7299.6830min+0.0099.68
PeptideMeter299.46, 99.9399.6928min-0.0599.74
Medutest199.9399.9325min+0.0899.85
VendorInvestigate199.7199.7132min-0.1199.82

This lot contributes 6 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.9099.68divergence +0.19 pp vs batch median
Total impurities (% area)not stated0.32
Largest single impurity (% area)not stated0.18
Water (%)5.06.14
Counter-ion (%)not stated5.57
Peptide content (%w/w)90.2not determined
Endotoxin (EU/mg)not statednot determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
Met sulfoxide (+16 Da)11 / 110.030.02–0.22
wild-type humanin (Ser14, −42 Da)11 / 110.040.02–0.15
truncated (1-20)8 / 110.170.04–0.45
deamidated (+1 Da)8 / 110.100.05–0.22
Section 7

What this rollup does not establish