AssayIndex
Growth-hormone axis peptides

IGF-1 DES (1-3)

DES(1-3)IGF-1 · des-tripeptide IGF-1 · C317H508N92O95S7 · monoisotopic 7365.7188 Da. The index holds 28 assay reports on this compound across 5 batches from 4 suppliers.

28 reports5 batchesmedian 98.53 %index spec 95.0 %
Section 1

Analytical fingerprint

Hand-authored chemistry. These properties describe the substance and do not change when a record is added.

DES(1-3)IGF-1 is produced by controlled N-terminal truncation, so the two informative impurities are the un-truncated parent at +343 Da and the over-truncated des(1-4) at −87 Da. Both are mass-diagnostic and neither is well resolved chromatographically. The same folding caveat as LR3 applies. Very thin coverage.

Molecular formula
C317H508N92O95S7
Monoisotopic mass
7365.7188Da
Average mass
7371.00Da
Residues
67
Nominal retention (RG-2, 30 min)
15.86min
Retention window
0.50min
Counter-ion as usually shipped
acetate
Typical label claims
0.1 mg · 1 mg
Analytical difficulty (index scale)
1.55 — hard
Purity is a defined quantity
YES
Section 2

Representative chromatogram

Drawn from this page's own medians. Not a scan, not an illustration, and not any single report.

01678335550336711 IGF-1 DES (1-3)15.86 min · 98.53 % 16.4418.91 same trace · ×200 vertical expansion, baseline-corrected · main peak off-scale reporting threshold 0.05 % area 05101520253035 Retention time (min) Response (mAU)
Figure 1. A representative IGF-1 DES (1-3) trace on the index reference method RG-2, constructed from this page's own numbers: the main peak carries the index median purity of 98.53 % area at the nominal retention time of 15.86 min, and each impurity peak carries the median area the index has observed for that named species at its characteristic retention offset. It is not a scan of any single report — every individual record's own chromatogram is on its own page. The lower panel is the same trace at a stated vertical expansion, baseline-corrected, so the impurities are visible; the main peak runs off-scale there by design. Baseline noise is seeded from the compound slug.
Section 3

What the index has observed

Arithmetic over the 28 records the index holds. Aggregates on this page are computed over the records the index holds, which are not a random sample of the material on the market. Lots that get tested are lots someone chose to test. Read every figure here as a description of this dataset rather than as an estimate of a population.

Median purity 98.53% n=28
Interquartile range 1.70pp n=28
Minimum 97.54% n=28
Maximum 99.93% n=28
Pass rate vs spec 100.0% n=28
Median recovery vs claim 98.0% n=15
Median water 3.94% n=28
Median |mass error| 2.5ppm n=21
02492.093.094.095.096.097.098.099.0100.092.00–92.25 %: n=092.25–92.50 %: n=092.50–92.75 %: n=092.75–93.00 %: n=093.00–93.25 %: n=093.25–93.50 %: n=093.50–93.75 %: n=093.75–94.00 %: n=094.00–94.25 %: n=094.25–94.50 %: n=094.50–94.75 %: n=094.75–95.00 %: n=095.00–95.25 %: n=095.25–95.50 %: n=095.50–95.75 %: n=095.75–96.00 %: n=096.00–96.25 %: n=096.25–96.50 %: n=096.50–96.75 %: n=096.75–97.00 %: n=097.00–97.25 %: n=097.25–97.50 %: n=097.50–97.75 %: n=597.75–98.00 %: n=498.00–98.25 %: n=298.25–98.50 %: n=298.50–98.75 %: n=398.75–99.00 %: n=199.00–99.25 %: n=299.25–99.50 %: n=199.50–99.75 %: n=499.75–100.00 %: n=4median 98.53 Purity (% area) Reports
Figure 2. Purity distribution across all 28 IGF-1 DES (1-3) records. Dashed line is this compound's median (98.53 %); the solid vertical is the index acceptance specification for the growth-hormone axis peptides class (95.0 %). Domain is fixed at 92–100 % on every purity histogram on this site so that compounds can be compared by eye — a wide distribution here is a hard compound, a narrow one is an easy one, and neither is a statement about the suppliers.
Section 4

By supplier

Suppliers with fewer than two purity records on this compound are omitted from the figure rather than drawn as a line. The full table, including the thin cells, is on the by-supplier page.

97.397.898.398.799.299.7100.1SWBSWB: Q1 97.73, median 97.94, Q3 98.23, n=14n=14SSASSA: Q1 98.94, median 99.28, Q3 99.68, n=9outlier 97.65n=9JEEPJEEP: Q1 99.75, median 99.75, Q3 99.79, n=3n=3WWBWWB: Q1 99.17, median 99.32, Q3 99.47, n=2n=2 Purity (% area)
Figure 3. IGF-1 DES (1-3) purity by supplier, ordered by coverage. The vertical line is the index acceptance specification. Boxes that overlap are suppliers this dataset cannot separate, and most of them overlap.

Full per-supplier table with n= caveats →

Section 5

Characteristic impurities and degradants

The left three columns are authored chemistry — what this molecule characteristically carries and where it elutes. The right three are what the index has actually reported.

Named speciesΔRT (min, RG-2)Δ mass (Da)Seen inMedian % areaMax % area
disulfide-scrambled isomer+0.58mass-identical100%0.320.74
des(1-4) over-truncate (−87 Da)-0.36-87.032100%0.191.09
full-length IGF-1 (+343 Da)+0.48+342.16693%0.171.22
aggregated dimer+3.05+7365.71989%0.211.65

Degradation pathways

  • disulfide scrambling
  • over-digestion to des(1-4) during production

Full impurity profile, with what each named species implies about the synthesis →

Section 7

Quarterly coverage

QuarterReportsMedian purityRange
2024-Q10n<3—
2024-Q2899.4598.51–99.93
2024-Q30n<3—
2024-Q40n<3—
2025-Q10n<3—
2025-Q20n<3—
2025-Q30n<3—
2025-Q4699.6897.65–99.83
2026-Q10n<3—
2026-Q21497.9497.54–98.74
2026-Q30n<3—

Quarter-by-quarter detail →

Section 8

Most recent records

The 25 most recent IGF-1 DES (1-3) records of 28.
ReportSupplierLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2026-042428SWBSWB-2601-Y5870PeptideMeter2026-Q298.743.82—Supplier-supplied1MARGINAL
AX-2026-042429SWBSWB-2601-Y5870Janoshik2026-Q298.114.0997.0Supplier-supplied1MARGINAL
AX-2026-042437SWBSWB-2601-Y5870Janoshik2026-Q297.724.1898.0Buyer-sourced1MARGINAL
AX-2026-042434SWBSWB-2601-Y5870Janoshik2026-Q298.004.05—Supplier-supplied1MARGINAL
AX-2026-042432SWBSWB-2601-Y5870Nordanalyt2026-Q297.564.26—Buyer-sourced2MARGINAL
AX-2026-042441SWBSWB-2601-Y5870Janoshik2026-Q298.554.26—Supplier-supplied2MARGINAL
AX-2026-042438SWBSWB-2601-Y5870Janoshik2026-Q297.943.70—Laboratory-retained2MARGINAL
AX-2026-042440SWBSWB-2601-Y5870Janoshik2026-Q297.884.0098.0Supplier-supplied1MARGINAL
AX-2026-042430SWBSWB-2601-Y5870PeptideMeter2026-Q297.953.81—Supplier-supplied2MARGINAL
AX-2026-042433SWBSWB-2601-Y5870PeptideMeter2026-Q298.323.4997.0Supplier-supplied2MARGINAL
AX-2026-042436SWBSWB-2601-Y5870Janoshik2026-Q297.684.3295.0Supplier-supplied1MARGINAL
AX-2026-042431SWBSWB-2601-Y5870Janoshik2026-Q298.274.14—Supplier-supplied1MARGINAL
AX-2026-042439SWBSWB-2601-Y5870PeptideMeter2026-Q297.763.79—Buyer-sourced1MARGINAL
AX-2026-042435SWBSWB-2601-Y5870VendorInvestigate2026-Q297.543.91—Buyer-sourced1MARGINAL
AX-2025-020605SSASSA-2509-Y7113Janoshik2025-Q497.656.48—Supplier-supplied1MARGINAL
AX-2025-019124JEEPJEEP-2510-M4682Nordanalyt2025-Q499.833.14107.4Supplier-supplied0PASS
AX-2025-018527WWBWWB-2505-N4242Janoshik2025-Q499.024.52—Supplier-supplied1MARGINAL
AX-2025-018528WWBWWB-2505-N4242Janoshik2025-Q499.624.5390.0Supplier-supplied2MARGINAL
AX-2025-019122JEEPJEEP-2510-M4682Janoshik2025-Q499.752.72—Supplier-supplied0PASS
AX-2025-019123JEEPJEEP-2510-M4682Janoshik2025-Q499.743.28104.0Supplier-supplied0PASS
AX-2024-005221SSASSA-2403-F6661PeptideMeter2024-Q299.283.4592.0Supplier-supplied0PASS
AX-2024-005220SSASSA-2403-F6661Medutest2024-Q299.933.91106.0Supplier-supplied0PASS
AX-2024-005222SSASSA-2403-F6661Janoshik2024-Q298.943.4699.0Buyer-sourced0PASS
AX-2024-005224SSASSA-2403-F6661Janoshik2024-Q299.633.96107.0Supplier-supplied1MARGINAL
AX-2024-005217SSASSA-2403-F6661Janoshik2024-Q299.684.52100.0Supplier-supplied1MARGINAL