AssayIndex

KP-2409-Y5476

NAD+ · 1000 mg declared · Zhuhai Kerui Biotechnology Co., Ltd. · manufactured 30 Sep 2024

CHARACTERISED
Lot code
KP-2409-Y5476
Supplier
KP — Zhuhai Kerui Biotechnology Co., Ltd.
Compound
NAD+
Compound class
Non-peptide adjuncts
Declared label claim
1000mg
Manufacture date
30 Sep 2024
Index quarter
2024-Q4
Independent assays
3
Laboratories involved
Janoshik, PeptideMeter, VendorInvestigate
Provenance mix
Buyer-sourced ×1 · Supplier-supplied ×2
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 3
Median purity 99.18% n=3
Spread (max − min) 0.88pp n=3
Standard deviation 0.447pp n=3
97.397.898.398.799.299.7100.1This lot (KP-2409-Y5476)This lot (KP-2409-Y5476): Q1 98.89, median 99.18, Q3 99.33, n=3n=3All NAD+All NAD+: Q1 98.35, median 98.88, Q3 99.38, n=48n=48 Purity (% area)
Figure 1. This lot's independent purity results against the whole NAD+ record set in the index. The vertical line is the index acceptance specification for the non-peptide adjuncts class, 97.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 3

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2024-005163KP-2409-Y5476Janoshik2024-Q499.4811.6298.2Supplier-supplied0FAIL
AX-2024-005164KP-2409-Y5476PeptideMeter2024-Q499.1811.7988.5Supplier-supplied1FAIL
AX-2024-005165KP-2409-Y5476VendorInvestigate2024-Q498.6011.9299.1Buyer-sourced0FAIL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik199.4899.4830min+0.0099.48
PeptideMeter199.1899.1828min-0.0599.23
VendorInvestigate198.6098.6032min-0.1198.71

This lot contributes 3 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)99.7399.48divergence +0.55 pp vs batch median
Total impurities (% area)0.270.52
Largest single impurity (% area)not stated0.22
Water (%)10.411.62
Counter-ion (%)not statedN/A
Peptide content (%w/w)not stated87.47
Endotoxin (EU/mg)not statednot determined
Method stated on certificateNOno method section — the result cannot be reconciled against any other
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
ADP-ribose (−121 Da)3 / 30.230.22–0.93
nicotinamide (−541 Da)3 / 30.200.08–0.32
nicotinamide mononucleotide (NMN, −331 Da)3 / 30.070.06–0.31
NADH (reduced, +2 Da)3 / 30.050.03–0.14
α-NAD anomer2 / 30.050.04–0.06
Section 7

What this rollup does not establish