AssayIndex

BCH-2506-G6608

Pemvidutide · 1.8 mg declared · Bachem Holding (Suzhou) Co., Ltd. · manufactured 16 Jun 2025

CHARACTERISED
Lot code
BCH-2506-G6608
Supplier
BCH — Bachem Holding (Suzhou) Co., Ltd.
Compound
Pemvidutide
Compound class
Incretin analogues and co-agonists
Declared label claim
2mg
Manufacture date
16 Jun 2025
Index quarter
2025-Q3
Independent assays
12
Laboratories involved
Janoshik, Medutest, PeptideMeter
Provenance mix
Buyer-sourced ×2 · Supplier-supplied ×9 · Laboratory-retained ×1
Section 1

Reproducibility across independent tests

Every report below is an observation of the same physical material. What they disagree about is measurement; what they agree about is the lot. The size of the disagreement is compared against what the contributing laboratories' own repeatability figures predict.

Independent assays 12
Median purity 97.99% n=12
Spread (max − min) 1.28pp n=12
Standard deviation 0.440pp n=12
96.797.397.898.499.099.6100.2This lot (BCH-2506-G6608)This lot (BCH-2506-G6608): Q1 97.55, median 97.98, Q3 98.35, n=12n=12All PemvidutideAll Pemvidutide: Q1 97.96, median 98.41, Q3 98.74, n=35outlier 99.93n=35 Purity (% area)
Figure 1. This lot's independent purity results against the whole Pemvidutide record set in the index. The vertical line is the index acceptance specification for the incretin analogues and co-agonists class, 96.0 % area. A narrow box on the top row against a wide box on the bottom row is the ideal reading: it means the disagreement between lots is much larger than the disagreement within this one.
Section 2

Member reports 12

Every report the index holds on this lot. Each is a page carrying its own chromatogram, mass spectrum, mass balance, provenance and caveats.

ReportLotLabQuarterPurity %Water %Recovery %ProvenanceFlagsResult
AX-2025-021260BCH-2506-G6608Janoshik2025-Q398.375.4893.0Supplier-supplied3MARGINAL
AX-2025-021261BCH-2506-G6608Medutest2025-Q398.705.41Supplier-supplied2MARGINAL
AX-2025-021262BCH-2506-G6608Medutest2025-Q397.985.2397.7Supplier-supplied2MARGINAL
AX-2025-021263BCH-2506-G6608Janoshik2025-Q398.345.2992.2Supplier-supplied2MARGINAL
AX-2025-021264BCH-2506-G6608Medutest2025-Q397.485.15Supplier-supplied2MARGINAL
AX-2025-021265BCH-2506-G6608Janoshik2025-Q397.535.58Buyer-sourced2MARGINAL
AX-2025-021266BCH-2506-G6608Janoshik2025-Q398.505.20Supplier-supplied2MARGINAL
AX-2025-021267BCH-2506-G6608PeptideMeter2025-Q397.425.57Supplier-supplied2MARGINAL
AX-2025-021268BCH-2506-G6608PeptideMeter2025-Q398.005.88Supplier-supplied2MARGINAL
AX-2025-021269BCH-2506-G6608Medutest2025-Q397.636.04107.2Buyer-sourced2MARGINAL
AX-2025-021270BCH-2506-G6608Janoshik2025-Q397.565.97Supplier-supplied2MARGINAL
AX-2025-021271BCH-2506-G6608Janoshik2025-Q397.996.33Laboratory-retained3MARGINAL
Section 3

By laboratory

Where more than one laboratory assayed this lot, the difference between them is a paired observation of their relative bias — the same material, the same time window, different instruments. Those pairs are what the index's bias estimates are built from.

LaboratoryReportsPurity results (% area)MedianGradientPublished bias (pp)Bias-adjusted
Janoshik698.37, 98.34, 97.53, 98.50, 97.56, 97.9998.1630min+0.0098.16
Medutest498.70, 97.98, 97.48, 97.6397.8125min+0.0897.73
PeptideMeter297.42, 98.0097.7128min-0.0597.76

This lot contributes 3 paired comparisons to the inter-lab analysis.

Section 4

The supplier's certificate for this lot

One number the supplier wrote, beside the median of the numbers other people measured on the same physical material. That comparison is only available because the index groups by lot.

FigureSupplier COAThis reportIndex note
Purity (% area)98.598.37divergence +0.51 pp vs batch median
Total impurities (% area)1.501.63
Largest single impurity (% area)not stated0.67
Water (%)5.05.48
Counter-ion (%)not stated6.90
Peptide content (%w/w)not stated86.81
Endotoxin (EU/mg)0.25not determined
Method stated on certificateYEScolumn, gradient and wavelength given
Section 5

Impurity fingerprint

The named impurities reported across this lot's assays, with how consistently each was seen. A fingerprint is what allows two lot numbers held by different companies to be identified as one bulk.

Named impurityReported inMedian % areaRange
[D-Aib2]-diastereomer12 / 120.550.25–1.04
truncated (3-39)12 / 120.970.59–1.61
aspartimide (−18 Da)12 / 120.210.11–0.27
des-EDA linker (−60 Da)12 / 120.190.13–0.25
Section 7

What this rollup does not establish