GIP (1-42) impurity profile
Every named species the index has reported alongside GIP (1-42), how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| GIP (3-42) DPP-4 truncate (−227 Da) | -0.31 | -227.116 | — | not observed | — |
| Met14 sulfoxide (+16 Da) | -0.75 | +15.995 | — | not observed | — |
| deamidated (+1 Da) | -0.40 | +0.984 | — | not observed | — |
| truncated (1-30) | -2.12 | -1379.694 | — | not observed | — |
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- N-terminal Tyr-Ala cleavage by residual DPP-4 activity in impure aqueous diluent
- Met oxidation