Adipotide impurity profile
Every named species the index has reported alongside Adipotide, how often, at what level, and what its presence implies about the synthesis or the handling. Reporting threshold is 0.05 % area; anything below it is invisible to this page and is silently added to the main peak.
Median total impurities
1.40%
n=16
Median largest single
0.72%
n=16
Worst single observed
1.97%
n=16
Named species observed
4 / 4
n=4
| Named species | ΔRT (min) | Δ mass (Da) | Seen in | Median % area | Max % area |
|---|---|---|---|---|---|
| open-chain (reduced disulfide, +2 Da) | -1.05 | +2.016 | 100% | 0.19 | 1.97 |
| truncated KLAKLAK repeat (−781 Da) | -1.62 | -781.512 | 100% | 0.32 | 1.97 |
| disulfide-scrambled isomer | +0.44 | mass-identical | 100% | 0.39 | 1.20 |
| trifluoroacetyl adduct (+96 Da) | +0.82 | +95.982 | 100% | 0.13 | 0.75 |
open-chain (reduced disulfide, +2 Da)
- Retention offset from the main peak
- -1.05 min on RG-2
- Mass difference
- +2.016 Da
- Reported in
- 16 of 16 records (100 %)
- Level when reported
- median 0.19 %, max 1.97 %
- Resolution requirement
- Baseline-resolved on the reference method.
truncated KLAKLAK repeat (−781 Da)
- Retention offset from the main peak
- -1.62 min on RG-2
- Mass difference
- -781.512 Da
- Reported in
- 16 of 16 records (100 %)
- Level when reported
- median 0.32 %, max 1.97 %
- Resolution requirement
- Baseline-resolved on the reference method.
disulfide-scrambled isomer
- Retention offset from the main peak
- +0.44 min on RG-2
- Mass difference
- mass-identical — chromatography only
- Reported in
- 16 of 16 records (100 %)
- Level when reported
- median 0.39 %, max 1.20 %
- Resolution requirement
- A gradient long enough to separate it. No mass spectrometer will.
trifluoroacetyl adduct (+96 Da)
- Retention offset from the main peak
- +0.82 min on RG-2
- Mass difference
- +95.982 Da
- Reported in
- 16 of 16 records (100 %)
- Level when reported
- median 0.13 %, max 0.75 %
- Resolution requirement
- Baseline-resolved on the reference method.
Degradation pathways
Degradants are a handling finding rather than a synthesis finding. A lot that shipped clean and arrived oxidised tells you about the courier, not the chemist.
- disulfide reduction
- aggregation of the cationic KLAKLAK domain