AssayIndex
Annotator

pyroglutamate

N-terminal cyclisation, the −17 Da species, and its ambiguity with aspartimide.

first seen 2025-Q10 records submitted3 annotations
Section 1

Contribution

Comments technically on records submitted by others. Annotations are signed and are not moderated for agreement.

Records submitted 0 n=0
Annotations 3 n=3
Median purity submitted suppressed n=0 n<3 — see individual records
Suppliers covered 0 n=0

This handle has submitted no records. Annotators comment on other people's submissions and are not required to submit.

Section 2

Annotations

Signed technical comments on records. The index does not moderate annotations for agreement with its own arithmetic, and several of these disagree with it.

AX-2026-042542
5.66 EU/mg but the material was passed through a sterile sterile filter. Some filters leach endotoxins; the measurement does not distinguish material from filter contribution.
AX-2025-020791
5.04 EU/mg but the material was passed through a sterile sterile filter. Some filters leach endotoxins; the measurement does not distinguish material from filter contribution.
AX-2024-004431
Purity 99.93 % and endotoxin 5.99 EU/mg are unrelated — purity measures synthesis quality, endotoxin measures fill-step water quality. The combination here is coherent and expected together.